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Chrono-immunotherapy''s current and future optimization strategies: immunotherapy timing in line with the circadian rhythm brings longer survival benefits 期刊论文

编号：

4F9E1C9C9AF477EF6529F50483083718
作者：

Liu, Daiwei#^[1,2]Li, Zhanlin*^[1]Cui, Huijuan(崔慧娟)^[3]Zhang, Hua^[4];Li, Hai^[5];Wu, Xiaoyuan^[1];
语种：

英文
期刊：

FRONTIERS IN IMMUNOLOGY ISSN：1664-3224 2026 年 17 卷 ; FEB 16
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关键词：

chrono-immunotherapy efficacy immunotherapy the circadian rhythm tumors
摘要：

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape for malignant tumors such as advanced lung cancer, but their efficacy is limited. In recent years, the circadian rhythm has provided a brand-new optimization strategy for immunotherapy. This perspective article aims to explore the potential mechanisms of the interaction between immunotherapy and circadian rhythms, reviews clinical evidence supporting that "time-of-day receipt of ICIs brings better therapeutic effects", and conduct an in-depth analysis of the current practical challenges of chrono-immunotherapy. And emphasize the potential of "chrono-immunotherapy" as a valuable therapeutic approach.
推荐引用方式
GB/T 7714：

Liu Daiwei,Li Zhanlin,Cui Huijuan, et al. Chrono-immunotherapy''s current and future optimization strategies: immunotherapy timing in line with the circadian rhythm brings longer survival benefits [J].FRONTIERS IN IMMUNOLOGY,2026,17.
APA：

Liu Daiwei,Li Zhanlin,Cui Huijuan,Zhang Hua,&Wu Xiaoyuan.(2026).Chrono-immunotherapy''s current and future optimization strategies: immunotherapy timing in line with the circadian rhythm brings longer survival benefits .FRONTIERS IN IMMUNOLOGY,17.
MLA：

Liu Daiwei, et al. "Chrono-immunotherapy''s current and future optimization strategies: immunotherapy timing in line with the circadian rhythm brings longer survival benefits" .FRONTIERS IN IMMUNOLOGY 17(2026).
入库时间：

2026/3/12 9:39:34
更新时间：

2026/3/12 9:39:34
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