Clinicopathological Characteristics and Prognosis of Breast Cancer in Young Women - A Single Center Study in a Developing Country

• 编号：
  EBD2F35C6FEFD6780037E315CE3C505B
• 作者：
  Sun, XiaoLiang(孙小亮)#^[1] Liu, Jun(刘军)^[1] Ji, HaoYang(纪浩洋)^[1] Yang, Meng(杨猛)^[1] Lu, Yao(鲁瑶)*^[1]
• 语种：
  英文
• 期刊：
  CANCER MANAGEMENT AND RESEARCH ISSN：1179-1322 2021 年 13 卷 (1601 - 1607)
• 收录：
   
• 关键词：
  young age breast cancer clinicopathological characteristics survival molecular subtypes TERTIARY CARE CENTER PROGESTERONE-RECEPTOR TREATMENT OUTCOMES ESTROGEN-RECEPTOR STATISTICS MANAGEMENT DIAGNOSIS SUBTYPES RISK
• 摘要：

  Objective: Breast cancer (BC) in young women tends to be more aggressive. This study highlights the clinicopathological features and outcomes of young breast cancer (YBC) patients in a developing country.
  Methods: Consecutive patients aged 35 years or younger with a pathologically confirmed diagnosis of breast cancer treated and followed up at our department were included. Medical records and follow-up databases were reviewed and documented.
  Results: The rate of breast conservation and reconstruction surgery is higher in YBC patients. YBC patients are more likely to have tumors over 5cm, high-grade, hormone receptor negative, triple negative and stage III than old patients. There was no statistically significant difference in the pathological type, lymph node metastasis, and HER2 status. The median follow-up time was 96 months. The disease-free survival (DFS) was significantly worse in the YBC group. However, the overall survival (OS) had no difference between the two groups.
  Conclusion: YBC patients had more aggressive pathological features, such as hormone receptor negative, triple negative, high-grade and advanced stage, and poorer DFS than the old counterparts.

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• 推荐引用方式
  GB/T 7714：
  Sun Xiaoliang,Liu Jun,Ji Haoyang, et al. Clinicopathological Characteristics and Prognosis of Breast Cancer in Young Women - A Single Center Study in a Developing Country [J].CANCER MANAGEMENT AND RESEARCH,2021,13:1601-1607.
• APA：
  Sun Xiaoliang,Liu Jun,Ji Haoyang,Yang Meng,&Lu Yao.(2021).Clinicopathological Characteristics and Prognosis of Breast Cancer in Young Women - A Single Center Study in a Developing Country .CANCER MANAGEMENT AND RESEARCH,13:1601-1607.
• MLA：
  Sun Xiaoliang, et al. "Clinicopathological Characteristics and Prognosis of Breast Cancer in Young Women - A Single Center Study in a Developing Country" .CANCER MANAGEMENT AND RESEARCH 13(2021):1601-1607.